产品货号：
Z21391
中文名称：
NEDD1抗体
英文名称：
Anti-NEDD1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NEDD1 Antibody |
| 指标别名 | GCP-WD;Neural precursor cell expressed developmentally down-regulated protein 1;NEDD1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | NEDD1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-NEDD1 was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the 343-667 region of human Nedd1. |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This product was adsorbed against GST from monospecific antiserum by immunoaffinity chromatography.This antibody reacts with endogenous Nedd1 protein.A BLAST analysis was used to suggest reactivity with Nedd1 from human,chimpanzee,macaque,marmoset,cattle,rat,and mouse based on a 100% homology with the immunizing sequence.Expect partial reactivity with Nedd1 from turkey,chicken,salmon,and Danio based on a 91% homology with the immunizing sequence.Cross-reactivity with Nedd1 from other sources has not been determined. |
| 浓度 | 40mg/mL by Refractometry |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.Microtubules are polymers of tubulin,which exist as heterodimers of alpha-tubulin and beta-tubulin.NEDD1 (neural precursor expressed,developmentally down-regulated protein1;also called GCP-WD) is a centrosomal protein that in mammals associates with the gamma-tubulin ring complex.Gamma-TuRC is critical for initiation,or nucleation,of the microtubule assembly.In association with this complex,NEDD1 plays an important role in targeting the gamma-TuRC complex to the site of microtubule nucleation and to the mitotic spindle.These events are essential for proper bipolar spindle formation and mitotic progression.Given the casual link between improper spindle function and tumorigenesis,characterization of Nedd1 function will be important to better understand various mechanisms underlying mitotic regulation,chromosome segregation,and cancer development. |
| Uniprot ID | Q8NHV4 |
| 推荐稀释比 | ELISA:1:100,000 WB:1:10,000 |
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